The Physics Of Splicing And Splicing - 1446 Words

3. Conclusions Compared to the molecular methods, the optics-based method offers several advantages such as the kinetic study of splicing and splicing inhibition, study of cis–trans alternative splicing, and rapid measurement of RNA splic-ing. The kinetics of pre-mRNA splicing and the effect of isoginkgetin on the splicing kinetics of the pre-mRNA at the single molecule level were analyzed. Because of their high temporal resolution and the ability to follow the splicing of individual pre-mRNA molecules, the optics-based methods provide the evidences about the relative stabilities of weakly stabilized RNA molecules and their lifetimes. This observation attributed to the formation of mRNA molecules that are the results of the splicing of pre-mRNA. The kinetics and course of monitoring of pre-mRNA splicing was directly reached by 10 min, and are not able to be monitored by the conventional assay. The appearance of scattering intensity and SERS spectra indicates the success in monitoring RNA spl icing; and the RNA splicing inhibition assay confirms that the optics-based methods can be used in study of RNA splicing inhi-bition. Moreover, the optics-based methods are able to detect alternative splicing, the RNA splicing for multi exon–intron pre-mRNA, generation of microRNA from intron of RNA processing events (e. g., maturation of microRNAs), and the siRNA maturation from the processing of host mRNAs, which are hot topics for the re-search of cancer, molecular immunology, andShow MoreRelatedRecent Advancements On HIV And Technology1400 Words   |  6 Pageswritten and people have long speculated upon what could be controlled with access to DNA-for example, height, hair color, eye color, athletic ability, and intelligence, just to name a few. Then a few years ago there became a new method for genetic â€Å"splicing† this method became known as CRISPR which stands for clustered regularly interspaced short palindromic repeat-associated system. This process is v ery precise and can act like a robot and seek out certain sequences which may be set up for a diseaseRead MoreSummary of the Universe in a Nutshell Essay1812 Words   |  8 Pages(E=MC2). His General Theory of Relativity pushed forth the idea that space and time were not independent, but rather connected in some fabric which is curved Link to the Course: The equation E=MC2 is looked at within the final unit of study for our physics course. In addition, this chapter looks heavily at the contradiction between the works of Einstein and Newton. Newton, and the laws which he advocated, are virtually the main fixture of our course. His perspective of a flat universe with a timelineRead MoreThe Benefits of Science and Technology3197 Words   |  13 PagesShocked at such a bold claim, many people overlook the benefits that such a discovery could endow on humanity. Instead, they say that by acting in such a manner, we humans are trying to play the role of God. However, according to Capra of Tao of Physics, Science is trying to find the basic stuff that constitutes the reality. This research has shed enormous amount of light on life. Though only a piece of the great jigsaw puzzle of life, it leads us one step closer to the whole picture. UnderstandingRead MoreSeminar-Report-on- Optical Fiber Communications7997 Words   |à ‚  32 Pages60 seconds. other delay in communication will be due to communication equipment switching and decoding, encoding the voice of the fiber. 6.2 Snells Law:- In order to understand ray propagation in a fiber. We need one more law from high school physics. This is Snells law. n1 sin .01 = n2 sin .02 Where n denotes the refractive index of the material.01/02 are angles in respective medium. Higher Refractive Index means denser medium. 1) When light enters in lighter medium from denser itRead MoreThe Engineering And Technology Field3957 Words   |  16 Pagesengineering/technology field encompasses a plethora of individual specializations. In this world of abounding technology and bustling development, one area of engineering remains almost entirely research-based: Aerospace Engineering. A perfect combination of physics, chemistry, mechanical engineering, and technology; it presents a new outlook towards the common engineer. Who hasn t wondered what really lies beyond our atmosphere? Aerospace engineering provides humanity with the only conceptualization of theRead More50 Harmful Effects of Genetically Modified (Gm) Foods14312 Words   |  58 Pagesincluding Michael Hansen, Ph.D., who states that Genetic engineering, despite the precise sound of the name, is actually a very messy process. IMPACT ON FARMING The decline in the number of farms is likely to accelerate in the coming years...gene-splicing technologies... change the way plants and animals are produced. Jeremy Rifkin Small Farm Livelihood and Survival 32. Decline and Destruction of Self-Sufficient Family Farms: In 1850, 60% of the working population in the US was engaged in agriculture